Which part of the stomach is associated with the majority of ulcers?

The lesser curvature of the stomach is associated with the majority of ulcers primarily due to its anatomical and physiological features. This area is more susceptible to the effects of gastric acid and the presence of peptic ulcers, which can arise from factors such as Helicobacter pylori infection, chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs), and excessive gastric acid production.

The lesser curvature contains more blood vessels, making it a critical site for ulcer formation, as ulcers can lead to significant bleeding in this area. Moreover, because the lesser curvature is adjacent to the esophagus and the duodenum, it experiences varying pressure and acid exposure, contributing to ulcer development.

Other sections of the stomach, while they can also develop ulcers, do not have the same prevalence or risk factors associated with ulcer formation as seen in the lesser curvature. For instance, the fundus and body of the stomach are generally less affected, as they are situated away from the regions that are most influenced by the factors leading to ulceration. The pylorus, which is the exit part of the stomach, can also be involved in ulceration but is often less frequently the primary site compared to the lesser curvature.